Among the lab values, which one is most decreased in patients with ITP?

In patients with Immune Thrombocytopenic Purpura (ITP), the most decreased value is the platelet count. ITP is characterized by an autoimmune response in which the immune system mistakenly destroys platelets, leading to thrombocytopenia (a low platelet count). While white blood cells, hemoglobin, and red blood cell counts may also present with variations, they are not primarily affected by ITP. The hallmark of this condition is the significant reduction in platelet count, which directly contributes to the bleeding tendencies observed in patients. Thus, recognizing that the primary laboratory finding in ITP is a low platelet count is crucial for understanding and diagnosing the disorder.