In patients with Cushing's syndrome, sodium levels are typically:

In Cushing's syndrome, the body produces excess cortisol, which can lead to a variety of metabolic effects, one of which is the retention of sodium. Increased cortisol can stimulate the renal tubules to reabsorb more sodium, leading to elevated sodium levels in the blood. This condition is also associated with fluid retention, which can further contribute to the increase in blood volume and potentially higher sodium concentration. Therefore, in patients with Cushing's syndrome, it is commonly observed that sodium levels are increased.

Understanding this relationship is important for recognizing the full spectrum of symptoms and the metabolic profile associated with Cushing's syndrome, which includes factors like hypertension and edema that accompany elevated sodium levels. It's crucial to identify these biochemical changes as part of the overall clinical picture in managing patients with this endocrine disorder.