In the context of HIV, what does the abbreviation "CD4" represent?

The abbreviation "CD4" stands for "Cluster of Differentiation 4." It refers specifically to a type of glycoprotein found on the surface of certain immune cells, including T-helper cells, which play a crucial role in the immune response.

In the context of HIV, CD4 cells are particularly important because the virus targets these cells to replicate, leading to a decrease in the immune system's ability to fight off infections and diseases. Monitoring CD4 counts is vital in the clinical management of HIV, as it helps determine the stage of the disease and the effectiveness of antiretroviral therapy.

Understanding the role of CD4 in HIV is essential for comprehending the disease's progression and the immune system's functioning, thereby emphasizing the importance of this abbreviation in the context of HIV and immunology.