What are the signs of theophylline toxicity related to gastrointestinal effects?

Nausea and vomiting are classic signs of theophylline toxicity, particularly when considering gastrointestinal effects. Theophylline is a methylxanthine that stimulates the central nervous system and has a narrow therapeutic range. When its levels exceed this range, various toxic effects can occur, including gastrointestinal disturbances.

Nausea and vomiting specifically arise as the body reacts to elevated levels of the drug. This response is due to the irritant effects that theophylline can have on the gastrointestinal lining and the body's overall reaction to increased drug levels. Healthcare providers monitor these symptoms closely, as they can help in adjusting the dosage of theophylline to avoid further toxicity.

While dehydration, abdominal cramps, and diarrhea can occur in general gastrointestinal disorders or reactions, they are not primary indicators specific to theophylline toxicity. Therefore, when evaluating the gastrointestinal signs of theophylline toxicity, nausea and vomiting are the most indicative symptoms that warrant attention.