What class of drugs is typically used to conservatively treat endometriosis?

The most appropriate class of drugs for the conservative treatment of endometriosis is androgens. This might seem surprising since androgens, typically associated with male hormones, can actually be beneficial in managing endometriosis symptoms. The use of androgens, such as Danazol, aims to create a pseudo-menopausal state by suppressing ovarian function, thereby reducing the levels of estrogen that feed endometrial tissue growth. This helps to alleviate pain and reduce the size of endometrial implants.

Androgens work by limiting the proliferation of endometrial tissue, making them an effective option for conservative management. While estrogens and progestins are also involved in the hormonal regulation of the menstrual cycle, their direct stimulation of endometrial tissue growth is not conducive to treating conditions like endometriosis. Antibiotics do not target the underlying hormonal imbalance or tissue growth associated with the disease, so they are not considered a treatment option for endometriosis itself, but rather address infections that could occur as a complication. Understanding the hormonal influences on endometriosis is key to appreciating why androgens are used in treatment.