What hormonal change typically causes symptoms of endometriosis to improve?

The improvement of endometriosis symptoms is typically associated with a decrease in estrogen. Endometriosis is characterized by the presence of endometrial-like tissue outside the uterus, which reacts to hormonal changes, particularly estrogen levels. When estrogen levels are high, this tissue can become larger and more active, leading to pain and other symptoms. Conversely, when estrogen levels decrease, the stimulation of this tissue is reduced, leading to a reduction in symptoms such as pelvic pain, discomfort, and other associated symptoms of endometriosis.

In clinical practice, a decrease in estrogen can occur during menopause or as a result of certain hormonal therapies aimed at managing endometriosis. These therapies work by suppressing estrogen production or blocking its effects, effectively providing relief for those affected by the condition.