What is considered a normal therapeutic blood level of theophylline?

Theophylline is a medication used primarily as a bronchodilator in the management of respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD). The normal therapeutic blood level of theophylline is crucial for ensuring both efficacy and safety in treatment.

A therapeutic range of 10 to 20 mcg/mL is recognized as optimal for most patients, as levels within this range are associated with effective respiratory support while minimizing the risk of toxicity. When theophylline levels fall below this range, it can lead to suboptimal therapeutic effects, leading to inadequate control of symptoms. Conversely, levels above this range can increase the risk of serious side effects, such as gastrointestinal disturbances, seizures, and cardiac arrhythmias.

Understanding this therapeutic range is essential for safe management of patients receiving theophylline therapy, as it guides dosing adjustments and monitoring to achieve the desired clinical outcomes without safety issues. Thus, the range of 10 to 20 mcg/mL is the correct answer.