What is critically important for administering Mestinon and other anticholinesterases?

Administering Mestinon and other anticholinesterases exactly on time is crucial due to the nature of their effects on the neuromuscular junction. This class of medication is used primarily for conditions like Myasthenia Gravis, where consistent drug levels in the bloodstream are imperative for optimal muscle function. If the medication is not administered on schedule, it can lead to significant fluctuations in muscle strength, resulting in either a worsening of symptoms or a possible myasthenic crisis.

Timing ensures that the medication maintains its therapeutic effect and prevents periods of muscle weakness or fatigue, which can be debilitating for the patient. Consequently, strict adherence to the prescribed schedule is necessary to manage the condition effectively.