What is the correct way to administer theophylline derivatives?

Theophylline derivatives are typically recommended to be taken with meals. This administration helps minimize gastrointestinal side effects such as nausea or irritation that can occur when the medication is taken on an empty stomach. The presence of food can also enhance absorption and improve the overall tolerability of the drug, ensuring that the patient can adhere to their treatment regimen more effectively.

Using soft drinks or administering the medication before exercise does not address the common concerns and potential side effects associated with theophylline derivatives. Additionally, taking these medications on an empty stomach may lead to increased discomfort and might impact the drug's effectiveness. Therefore, administering theophylline derivatives with meals is a well-accepted practice to balance efficacy with patient comfort.