What is the effect of Codeine if taken without adequate water intake?

Codeine is an opioid analgesic that is known for its potential to cause constipation as a side effect. When taken, codeine inhibits gastrointestinal motility, which slows down the movement of the intestines and can lead to harder, more difficult-to-pass stools. Adequate water intake is crucial for maintaining hydration and ensuring proper digestion and bowel function. Without sufficient water, the stool can become drier and more compact, making it even harder to eliminate. This exacerbates the natural constipating effect of codeine, making it a common concern for individuals who are prescribed this medication.

In contrast, other options do not directly relate to the effects of insufficient water intake when using codeine. While diarrhea can be a side effect of some medications, it is not associated with codeine use. Codeine typically does not increase pain; rather, it is used to manage pain. Similarly, the effectiveness of the drug is generally not diminished by water intake, although hydration may play a role in the overall comfort and health of the patient.