What is the main role of chelating agents in lead poisoning treatment?

Chelating agents play a critical role in the treatment of lead poisoning primarily by increasing the excretion of heavy metals. When a chelating agent is administered, it binds to lead and other heavy metals present in the bloodstream, forming a stable complex. This complex is then excreted through the kidneys, effectively reducing the toxic burden of lead in the body.

Lead is a toxic metal that can cause significant health problems, and simply reducing its absorption or managing symptoms is not enough for effective treatment. The mechanism of action of chelating agents focuses on removing the lead that has already entered the body, which is why increasing excretion is the primary therapeutic goal in cases of lead poisoning.