What is the most commonly administered loop diuretic to reduce ICP?

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The most commonly administered loop diuretic to reduce intracranial pressure (ICP) is Lasix, also known by its generic name, furosemide. Loop diuretics like Lasix function by inhibiting the sodium-potassium-chloride co-transporter in the ascending loop of Henle in the kidneys. This action leads to increased excretion of sodium and water, which reduces blood volume and, subsequently, can help decrease elevated ICP.

In the context of critical care and neurology, the management of elevated ICP often requires rapid and effective interventions. Lasix is favored due to its potency and well-established track record in both acute and chronic management of fluid overload states, including situations where ICP is a concern.

Other options such as spironolactone and amiloride are potassium-sparing diuretics, which are not typically used for the immediate reduction of ICP. While they are effective in managing fluid retention and heart failure, their mechanism of action and slower onset do not make them the first choice in acute scenarios. Bumetanide, another loop diuretic, is indeed effective but not as commonly used as Lasix, which is more readily available and better studied in this specific context.

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