What should patients taking Carafate be advised regarding other medications?

Patients taking Carafate, which contains sucralfate, should be advised to administer other medications separately from Carafate. This is important because Carafate forms a protective barrier over the stomach and can interfere with the absorption of other medications if taken at the same time. When Carafate is ingested, it can bind to and disrupt the absorption of other drugs, leading to reduced efficacy of those medications. Therefore, to ensure optimal therapeutic effects of all medications involved, it is essential that they be spaced out, allowing sufficient time for Carafate to coat the stomach before other drugs are taken. This recommendation helps to maintain the effectiveness of the medication regimen while providing the protective benefits Carafate offers.