Which drug is commonly used for post-operative analgesia in patients after craniotomy?

The commonly used drug for post-operative analgesia in patients after craniotomy is oxycodone. This opioid analgesic is often favored in post-operative settings, particularly after surgical procedures such as craniotomy, due to its effectiveness in managing moderate to severe pain.

Post-operative pain management is critical, especially in neurosurgery, where patients may have heightened sensitivity to pain, and precise pain control can contribute to better recovery outcomes. Oxycodone, being an opioid, works by binding to specific receptors in the brain and spinal cord, effectively altering the perception of pain and providing relief. It is typically administered when a stronger pain management approach is warranted, as is often the case following significant surgeries.

While acetaminophen and ibuprofen are non-opioid analgesics that may be used for less severe pain relief, they are not as effective for higher levels of post-operative pain. Codeine, while an opioid, usually provides lower analgesic potency compared to oxycodone, making it less suitable for severe post-operative pain management. Therefore, oxycodone is the preferred choice due to its stronger pain-relieving properties required in a post-craniotomy setting.