Which of the following is NOT a symptom of HIV disease?

While confusion can be associated with advanced stages of HIV or related opportunistic infections, it is not a primary symptom of HIV disease itself. Instead, anorexia, night sweats, and fatigue are more typical manifestations. Anorexia refers to the loss of appetite and is common in HIV due to various factors, including metabolic changes and psychological effects. Night sweats are frequent and often indicate immune system activation or the presence of infections. Fatigue can be persistent and is also a common symptom experienced by individuals with HIV due to the body's ongoing fight against the virus and associated conditions. Therefore, confusion is less directly linked to the early or primary symptoms of the disease, highlighting why it is the correct choice in this scenario.