Which of the following organs is least affected by hypertension?

The liver is considered the organ least affected by hypertension due to its unique vascular structure and capacity for compensation. Unlike the kidneys, brain, and eyes, which have highly sensitive tissues that can sustain damage from high blood pressure, the liver is more resilient to such changes.

While elevated blood pressure can indirectly influence liver health by affecting overall circulation and potentially leading to conditions such as fatty liver disease, the direct impact of hypertension on liver function is generally less pronounced. The liver is designed to handle fluctuations in blood flow and pressures, and it has a greater ability to regenerate and maintain its function even in adverse conditions compared to the other listed organs.

In contrast, the kidneys can experience damage leading to chronic kidney disease, the brain can suffer from strokes and other neurovascular events, and the eyes can develop conditions such as hypertensive retinopathy if blood pressure remains uncontrolled. Each of these organs has a direct correlation with hypertension, making them more susceptible to damage compared to the liver.