Which part of the intestines is primarily affected by Crohn's disease?

Crohn's disease primarily affects the terminal part of the small intestine, known as the ileum, which is part of the distal small intestine. This condition is classified as an inflammatory bowel disease that can cause inflammation anywhere along the gastrointestinal tract, but has a significant predilection for the ileum. The inflammation can lead to various symptoms, such as abdominal pain, persistent diarrhea, weight loss, and malnutrition due to the critical role of the ileum in nutrient absorption.

While Crohn's can affect other areas of the intestines, including parts of the colon, its most characteristic and commonly affected site is indeed the terminal ileum. This specificity is pivotal for diagnosis and treatment strategies, emphasizing the need to focus on this area when managing the disease. Understanding this anatomical preference aids healthcare providers in recognizing symptoms and tailoring patient care accordingly.