Which two classes of drugs are known to cause photophobia?

Photophobia, or light sensitivity, can be a side effect associated with various drug classes. Mydriatics, which are agents that dilate the pupils, can lead to photophobia due to the increased light entering the eye when the pupils are widened. This dilation may hinder the eye's ability to constrict in bright light, causing discomfort.

Anticholinergics, another class included in this answer, also have effects that can lead to photophobia. These medications inhibit the action of acetylcholine in the eye, which can affect the ability of the pupil to respond appropriately to light conditions, further contributing to light sensitivity.

The other drug classes mentioned do not typically lead to photophobia. Beta-blockers and miotics have different mechanisms of action and effects on the eye. Antihistamines and diuretics may have various side effects, but they are not primarily associated with causing photophobia. Prostaglandins and carbonic anhydrase inhibitors are used mainly for glaucoma and do not typically result in symptoms of light sensitivity either.