Which two organs are primarily affected by cystic fibrosis?

The two organs primarily affected by cystic fibrosis are the lungs and pancreas. Cystic fibrosis is a genetic disorder that leads to the production of thick, sticky mucus that can obstruct airways and various ducts in the body.

In the lungs, this thick mucus traps bacteria, leading to chronic lung infections, inflammation, and respiratory issues. Over time, this can cause significant damage to lung tissue and impair the ability to breathe effectively, resulting in respiratory failure if not managed properly.

In the pancreas, the thickening of secretions can block the pancreatic ducts, preventing digestive enzymes from reaching the intestines. This obstruction can lead to malabsorption of nutrients, resulting in nutritional deficiencies and other gastrointestinal problems.

Understanding the specific impact of cystic fibrosis on these two organs is crucial for diagnosis and management of the disease, as treatments often focus on improving lung function and managing digestive complications.