Who has the highest incidence of Buerger's disease?

Buerger's disease, also known as thromboangiitis obliterans, is most commonly associated with tobacco use, specifically among smokers. The disease primarily affects the small and medium-sized blood vessels, leading to reduced blood flow to the limbs. The characteristic demographic most affected by Buerger's disease includes young male smokers, typically between the ages of 20 and 40. This condition is strongly linked to smoking habits, as the chemicals in tobacco can cause vascular inflammation and contribute to the development of this debilitating disease.

While non-smokers and individuals over 60 are also at risk for various vascular diseases, they do not exhibit the same high incidence of Buerger's disease as smokers. Furthermore, while females can develop the disease, the overall higher prevalence in smokers, particularly young males, solidifies the association between tobacco use and Buerger's disease incidence. Understanding this relationship is crucial in both identifying at-risk populations and in preventive measures aimed at reducing tobacco use.